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Testosterone, testing and treatment
Understand testosterone doses, mg/mL concentrations, U-100 syringe marks and needle gauges, with worked examples and links to the TRT dose calculator.
Read articleWhy TRT raises hematocrit, what human studies show about clots and stroke, and how hydration, altitude, iron stores and blood donation change the discussion.
Read articleTRT and SGLT2 medicines can both raise blood counts. Explore the combination studies, newer clotting evidence and the monitoring questions that help preserve treatment benefits.
Read articleA lower hematocrit after donation does not prove iron stores have recovered. Learn how ferritin, hemoglobin and fatigue can diverge, and what a coordinated TRT follow-up should address.
Read articleMuscle gain can complicate creatinine results on TRT, but cystatin C is not a perfect referee. Learn how blood markers, urine testing and measured filtration help clarify kidney health.
Read articleAcne and scalp thinning can appear during TRT, but DHT is only part of the explanation. Explore human evidence, diagnostic differences and the trade-offs of skin and hair treatments.
Read articleNew studies link prescription testosterone with tendon injuries, but the findings vary. Explore absolute risks, the 2025–2026 evidence and what it means for training, symptoms and care.
Read articlePrednisone and other glucocorticoids can complicate testosterone assessment. Learn what human studies show, how adrenal suppression differs and where TRT fits in a coordinated treatment plan.
Read articleAn unexpected testosterone result can reflect assay interference. Learn how biotin, antibodies and laboratory methods affect interpretation and what independent confirmation can resolve.
Read articleTRAVERSE reported more atrial fibrillation despite reassuring major cardiovascular results. Explore the rhythm signal, conflicting studies and what new palpitations need.
Read articleTestosterone can promote fluid retention, but swollen ankles have several possible causes. Learn which patterns need prompt assessment and how clinicians investigate edema.
Read articleLearn how testosterone doses overlap, when TRT reaches steady state, and how injection frequency affects peaks, troughs, blood tests and possible side effects.
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