Metformin and healthy aging: who might benefit, and what about exercise?
Metformin helps many people with diabetes, but healthy-aging claims need separate evidence. Read MILES, MASTERS, newer function trials and the exercise tradeoffs.
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Metformin helps many people with diabetes, but healthy-aging claims need separate evidence. Read MILES, MASTERS, newer function trials and the exercise tradeoffs.
Read articleSenolytic research now includes human trials in lung, bone, kidney and liver disease. Explore what cell clearance means, the strongest findings and the questions still open.
Read articlePartial cellular reprogramming has reached an early human eye trial. Understand ER-100, the October 2026 observations, cell identity, visual outcomes and the safety questions.
Read articleCompanion-dog studies can test lifespan alongside mobility, cognition and quality of life. Explore TRIAD, earlier rapamycin findings and the separate Loyal drug programs.
Read articleRegular sleep timing is linked with healthier aging, but the evidence is more nuanced than a bedtime score. Explore circadian biology, clinical studies and sleep problems worth assessing.
Read articleBiological age tests can reveal useful patterns, but a younger score is not proof of longer life. Learn what different clocks measure, what recent trials found and how to interpret change.
Read articleHuman fasting studies now measure cellular recycling more directly. Explore what autophagic flux, weight-loss trials and aging biomarkers show, and where the evidence still stops.
Read articleProtein needs depend on age, activity, appetite and health. Read the human evidence on muscle function, plant foods, growth signals and kidney disease without reducing longevity to a single target.
Read articleExplore what human studies show about fiber, fermented foods, gut microbes and inflammation, including newer trials and what their results mean for healthy aging.
Read articleSauna studies offer encouraging clues about circulation, but controlled trials give mixed results. Learn what heat can reasonably add, how methods differ and where practical limits matter.
Read articleInflammation trials show both real cardiovascular benefits and important failures. Learn what CANTOS, colchicine and the 2026 ZEUS update mean for biomarkers, safety and healthy aging.
Read articleTelomeres support tissue renewal, but longer is not always healthier. Human genetics, clinical testing and peptide research reveal why telomere length cannot serve as a simple longevity target.
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